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OpenResearch Grant

Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)

Funded by:
The National Institutes of Health (NIH)
Grant Amount
USD: 40,000,000Program Funding
Deadline
Nov 10, 2026
190 days remaining
Est. Awards
4 Grants
Funding Purpose
Clinical TrialsApplied Research
Subjects
MedicineNeuroscience

Description

Amyotrophic Lateral Sclerosis (ALS) Research Funding Opportunity

This opportunity is provided by the National Institute of Neurological Disorders and Stroke (NINDS) through the National Institutes of Health (NIH).

Opportunity Overview

This funding opportunity supports research related to Amyotrophic Lateral Sclerosis (ALS). The goal is to advance scientific understanding and therapeutic development for this devastating neurodegenerative disease.

Funding Mechanism: Grant Funding

Funding Agency: National Institutes of Health (NIH) / NINDS

Application Deadline: (Check official NIH/Grants.gov for current deadlines)

Eligibility and Scope

This funding is targeted toward research investigating the underlying mechanisms, pathophysiology, and potential treatments for ALS.

Eligible Applicants:

  • Academic and research institutions.
  • Principal Investigators (PIs) with expertise in neurobiology, genetics, or neuromuscular disorders.

Scope of Research:

Research proposals should address areas such as:

  • Genetic risk factors and mutations in ALS.
  • Protein aggregation and misfolding pathways.
  • Neuroinflammation and glial cell involvement.
  • Development of novel therapeutic targets (e.g., small molecules, gene therapy).

Key Requirements and Guidelines

All submissions must adhere to the guidelines set forth by the NIH and the specific funding mechanism (e.g., R01, R21).

Mandatory Components:

  1. Detailed Specific Aims outlining the research objectives.
  2. Comprehensive Research Strategy detailing methodology and expected outcomes.
  3. Biosketches and institutional support letters.
  4. Budget justification detailing personnel, equipment, and supplies.

Review Criteria:

Proposals will be evaluated based on the significance of the problem, the innovation of the proposed approach, the investigator's expertise, and the potential impact on ALS research.

How to Apply

Disclaimer: This is a summary guide. Applicants MUST use the official NIH Grants.gov portal for the most current and authoritative instructions.

  1. Review Funding Opportunity Announcement (FOA): Locate the specific RFA/PA for ALS research on the NIH website.
  2. Prepare Materials: Assemble all required documents (Biosketches, Facilities Description, etc.).
  3. Submit Online: Submit the complete package through the Grants.gov system before the stated deadline.

Disclaimer: This content is for informational purposes only and does not constitute official funding advice. Always refer to the official NIH/NINDS guidelines for the current funding cycle.

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Grant Timeline

Submission Deadline

Nov 10, 2026

Eligibility & Coverage

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UniversitiesNon-profit organizations (NGOs)For Profit Organizations
All Career Level
AnguillaAntarcticaAntigua and BarbudaArubaAustralia
AnguillaAntarcticaAntigua and BarbudaArubaAustralia
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Additional Details

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