Research Grant Opportunity: Development of PET Tracers for Neurodegenerative Diseases
This opportunity supports innovative research focused on developing novel Positron Emission Tomography (PET) tracers for the early and accurate diagnosis of neurodegenerative disorders.
Project Overview
The primary goal of this research is to advance the diagnostic capabilities for diseases such as Alzheimer's, Parkinson's, and related dementias. This involves synthesizing, characterizing, and pre-clinically testing novel radiolabeled tracers that bind specifically to pathological protein aggregates (e.g., amyloid-beta plaques, tau tangles, alpha-synuclein deposits) in the living brain.
Successful outcomes will pave the way for non-invasive, quantitative imaging biomarkers, enabling earlier intervention and more precise staging of these complex diseases.
Eligibility and Scope
Investigators are encouraged to submit proposals detailing expertise in radiochemistry, molecular biology, neuroimaging, and preclinical animal models.
Eligible Applicants:
- Academic researchers affiliated with recognized research institutions.
- Biotechnology companies with established research divisions.
Scope of Work:
- Target Identification: Selecting appropriate pathological targets for imaging.
- Radiotracer Synthesis: Developing scalable and efficient synthetic routes for novel tracers.
- In Vitro Validation: Assessing binding affinity and selectivity using cell culture models.
- In Vivo Assessment: Testing tracer biodistribution, pharmacokinetics, and target engagement in relevant animal models.
Funding Details
Funding Period: 3 Years
Maximum Award Amount: Up to $1,500,000 USD
Submission Deadline: October 30, 2024
Note: Detailed budget guidelines and required institutional matching funds must be addressed in the proposal narrative.
Submission Guidelines
Proposals must be submitted electronically via the designated grant portal. The submission package must include:
- A detailed Research Proposal (Max 25 pages).
- A comprehensive Budget and Budget Justification.
- Curriculum Vitae (CVs) for all Key Personnel.
- Letters of Support from collaborating institutions (if applicable).
Review Criteria: Scientific Merit (40%), Feasibility and Methodology (30%), Investigator Capability (20%), and Potential Impact (10%).
Contact Information
For technical questions regarding the submission portal, please contact: grants@neuroimagingresearch.org
For scientific inquiries, please contact: scientific.inquiries@neuroimagingresearch.org