Overview

The upcoming Cell Symposia on "Chemical Biology in Drugging the Undrugged," held in partnership with the University of California, San Francisco (UCSF), will take place from September 30 to October 2, 2024, in San Francisco, CA, USA. This symposium aims to explore and advance the frontiers of drug discovery and development, particularly focusing on targets previously deemed "undruggable."

Objectives

The symposium seeks to highlight the transformative potential of modern chemical and biological tools in drug development. By redefining “undruggable” targets as “not yet drugged,” this event aims to inspire a shift in perspective that can lead to significant breakthroughs in both basic biological research and therapeutic innovation.

Key Topics

• Expanding the Druggable Proteome: Exploring new molecular targets that can be modulated by chemical compounds.

• Emerging Proximity-Based Drug Discovery: Innovative approaches to bring drugs in close proximity to their targets.

• Immuno-Oncology: Targeting Tumor Microenvironment: Strategies to modulate the immune environment within tumors for therapeutic benefit.

• Nucleic Acid-Based Therapeutics: Advancements in RNA and DNA-based treatments.

• Chembiol Tools: Biosensors and Biological Imaging: The latest tools for visualizing and measuring biological processes.

Speakers

The event will feature keynote speaker Kevan Shokat, along with prominent researchers including Michelle Arkin, Marianne Ashford, Yimon Aye, Miklos Bekes, Robert Blelloch, Ling-Ling Chen, Danette Daniels, Julian Downward, Fleur Ferguson, Eric Fischer, Ryan Flynn, Nathanael S. Gray, Ming Hammond, Yamuna Krishnan, Lingyin Li, Jennifer Petter, Ingrid E. Wertz, Pete Wildes, and Zhong-Yin Zhang.

Organizers

The symposium is organized by leading experts in the field:

• Michelle Arkin, University of California San Francisco, USA

• Nathanael S. Gray, Stanford University, USA

• Mishtu Dey, Editor-in-chief, Cell Chemical Biology

• Zhaodong Li, Scientific editor, Cancer Cell

Benefits of Attendance

Attendees will gain access to cutting-edge research presentations, networking opportunities with leading scientists, and discussions on future directions in drug discovery. The registration fee includes access to all symposium sessions, the conference app, welcome reception, mid-session refreshments, and lunch as scheduled in the program.

Supporting Publications

• Cell Chemical Biology

• Cancer Cell

• Cell

• Trends in Cancer

• Molecular Cell

• Cell Reports